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Thyroid disease may be associated with a variety of psychiatric disorders, including mild depression and anxiety [1]. In previous studies, patients with thyroid dysfunction had a higher prevalence of mood and anxiety disorders compared to other psychiatric disorders [2]. Studies have also found that 20.5% of patients with hypothyroidism have depression, while anxiety disorders have been identified in 30–40% patients with acute hypothyroidism [3-5]. The association between depression and thyroid hormones has been previously examined. Patients with clinically significant deAssociation between Depression, Daytime Sleepiness, and Thyroid Function in Patients with Thyroid Hormone Replacement Therapy