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The article is aimed at disclosing the theoretical approaches and substantiating the methodological principles of development of high-tech pharmaceutical production (HTPhP) of Ukraine in the conditions of European integration. The author identifies the nature of development of HTPhP in developing countries and displays the related obstacles; the new form of dependence on the supply of intermediate goods for production and finished medicines for healthcare, manifested in the context of the COVID-19 pandemic, is specified. It is noted that the key determinant of obtaining sustainable competitive advantages of the Ukrainian HTPhP should be the construction of strategic networks with key stakeholders of the national innovation system on the part of companies. It is substantiated that the involvement of TNCs technologies can be a catalyst for the modernization of Ukrainian pharmaceuticals, provided that this process is accompanied by an active policy of the State. It is shown that despite the fact that Ukraine has created a regulatory framework, which generally relies on the guidelines defined by the EU and WHO, Ukraine continues to increase its dependence on imports of pharmaceutical goods. It is determined that the current normative acts in Ukraine regulate legal relations in the pharmaceutical sector, but do not define either priorities for pharmaceuticals or measures for their implementation. Endogenous barriers and exogenous threats impeding the development of HTPhP of Ukraine are identified. It is recommended to balance the interests of consumers and manufacturers with the interests of the State when choosing the benchmarks of the HTPhP development policy of Ukraine. In view of the development of pharmaceuticals, attention is paid to a significant role of consciousness of doctors and patients regarding the quality and efficacy of medicines produced in Ukraine; mental and value changes, transformation of informal institutions; improvement of framework conditions for innovation.

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The Theoretical Approaches and Methodological Principles for Development of Ukrainian Pharmaceutical Production in the Conditions of European Integration