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Kidney Disease is associated with the highest rate of adverse maternal-fetal outcomes than any other pre-existing medical condition1. Chronic Kidney Disease (CKD) affects up to 6% of women of childbearing age in high-income countries and is estimated to affect 3% of pregnant women. In advanced CKD, pregnancy may precipitate the need for dialysis2. Reproductive health in women with CKD is very complex, influenced by the effects of kidney disease and drug therapy used3. CKD reduces fertility due to many factors, such as the progressive dysfunction of the hypothalamic-pituitary-gonadal axis and the decrease of renal clearance of prolactin, leading to anovulation4, and as CKD worsens, so does fertility5.

Clinical perspectives to improve pregnancy outcome in women undergoing chronic hemodialysis