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To improve the adaptation of the pancreatic microflora to changes in the diets of calves and for the rational use of feed, in intensive cultivation, it is desirable to change the composition of feed probiotic supplements according to the age of the animals.Each age group of calves responds differently to live weight gain on probiotic feed additives. Feed supplement Immunobacterin-D containing Bacillus subtilis, Bacillus licheniformis has a positive effect on natural resistance, increases the average daily gain and has a preventive effect on diseases of the digestive tract of calves. But for 2 months of continuous feeding can cause suppression of natural resistance of some animals. When baker's yeast is added to the feed additive (B. subtilis, B. licheniformis 1 × 1010 CFU / g, Sascharomyces cerevisiae 1 × 109 CFU / g), the dry form of the product makes it possible to feed it with compound feed. The use of immunobacterin-D with yeast in 3-month-old calves in experimental animals in the clinical examination for fatness and coat condition looked better. Calves of the experimental group during this period added in increments of 276 g in the previous month, the arithmetic mean of the average daily gain of live weight was 820 ± 180 g, and in the current 1096 ± 90 g, which indicates a positive effect of yeast (especially live) on the productivity of calves at this age.For studies on heifers in a farm with lower average daily gains in live weight, we received a smaller percentage increase in gains with the use of feed probiotic supplement Immunobacterin-D with baker's yeast. When adding to the feed additives at a dose of 40 g and 20 g to heifers 350–400 kg live weight of the animal had an average daily gain of live weight in the first group of 500 ± 17 g, in the second 440 ± 30 g, and in the control 414 ± 12 g, which is 20.8 and 6.3 % more than in the control group. The use of yeast in feed additives confirms the pattern of increasing the percentage of additional average daily gain. That is, with higher average daily gains, we get a higher percentage of additional growth from feeding a probiotic feed additive containing baker's yeast.

PROBIOTIC FEED ADDITIVES - PERSPECTIVES OF RATIONAL FEEDING OF CALVES