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Background: Physical stress in the form of increase in the maximum body workload lead to oxidative stress. Oxidative stress is the condition of imbalance between free radicals and antioxidants. This is indicated by decrease in oxygen saturation (SpO 2 ). Kaliandra honey is type of honey that is widely consumed in Indonesia. Kaliandra honey content of high antioxidant that is believed to prevent oxidative stress. Materials and Methods: Twelve male rats (age 2 months: body weight 170-200 g) were recruited and assigned to perform physical stress model with keliandra honey consumption. Type experimental laboratories research using randomized post test control group design. There are four group of rats; normal variation (NC), physical stress (PC), giving honey 24 hours before physical stress (T1) giving honey 2 hours before physical stress (T2). Result: The mean of SpO 2 rats was within under normal classification. The results showed that the mean SpO 2 level of NC was significant compared to the other  group PC, T1 and T2 while there was no significant difference between PC, T1 and T2. Conclusion: Physical stress success to create blocakge in the blood flow to the muscles. Proven with low oxygen saturation levels. The decrease in oxygen saturation to the muscles leads to an increase in free radical formation. The consumption of kaliandra honey and did not succeed in preventing oxidative stress. Keywords: physical stress, oxygen saturation, honey, antioxidant, oxidative stress

THE EFFECTS OF KALIANDRA HONEY (Calliandra Calothyrsus) ON OXYGEN SATURATION (SpO2) IN RATS EXPOSED TO PHYSICAL STRESS