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.  Chagas disease is endemic in the state of Morelos. The available medication is benznidazole, however adherence to treatment is generally not monitored by medical personnel to verify the accomplishment. Objective . To evaluate the adherence to therapeutic treatment and the risk factors associated with its compliance and the registry of adverse effects in patients with Chagas disease in the state of Morelos. Material and Methods . Follow-up study in 20 chronic asymptomatic patients. Adherence was assessed using the Morisky-Green structured test, a questionnaire was applied to record the risk factors related to adherence to treatment, home visits were made to the cases, and personalized interviews were conducted in 8 cases to obtain information on positive and negative factors associated with treatment. Results . Sixty five percent of patients were adherent to treatment and 35% were non-adherent due to non-compliance behaviors. Seven cases (35%) had some type of adverse reaction to the drug that did not warrant treatment discontinuation, except for two cases that had severe reactions. Statistical analysis of the variables in adherent and non-adherent cases showed no statistical association between adherence and variables of socioeconomic level, school level, access to medical service, marital status, age and sex. Conclusions .  Adherence assessment in patients with a confirmed diagnosis of Chagas' disease in the state of Morelos provided information to follow up on treatment compliance and record of adverse effects. Introduccion. La enfermedad de Chagas es endemica en el estado de Morelos.  El medicamento disponible es el benznidazol, sin embargo generalmente la adherencia al tratamiento no es vigilado por el personal medico para verificar su cumplimiento. Objetivo. Evaluar la adherencia al tratamiento terapeutico y los factores de riesgo asociados con su cumplimiento y el registro de efectos adversos en pacientes con enfermedad de Chagas del estado de Morelos. Material y Metodos. Estudio de seguimiento en 20 pacientes asintomaticos. La adherencia se evaluo mediante la aplicacion del cuestionario estructurado de Morisky-Green, se aplico un cuestionario para registrar los factores de riesgo relacionados con el apego al tratamiento, se hicieron visitas domiciliarias y se hicieron entrevistas personalizadas a 8 casos para obtener informacion sobre factores positivos y negativos asociados al tratamiento. Resultados. El 65% de los pacientes fueron adherentes al tratamiento y 35% fueron no adherentes debido a conductas de incumplimiento. Siete casos (35%) presentaron algun tipo de reaccion adversa al medicamento que no amerito la suspension del tratamiento, excepto dos casos que tuvieron reacciones severas. El analisis estadistico de las variables en los casos adherentes y no adherentes no mostro asociacion estadistica entre la adherencia y las variables de nivel socioeconomico, escolaridad, acceso al servico medico, estado civil, edad y sexo. Conclusiones. La evaluacion de la adherencia en pacientes con diagnostico confirmado de enfermedad de Chagas del estado de Morelos, aporto informacion para dar seguimiento al cumplimiento del tratamiento y registrar los efectos adversos.

Adherencia al tratamiento terapéutico en pacientes con enfermedad de Chagas del Estado de Morelos.