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At interaction of hydrogen sulphide with piperidino-2,3-epoxyprorane there is formed piperidino-2hydroxypropanthiol-3. The latter reacts by Mannich with formaldehyde and secondary aliphatic and heterocyclic amines, as well with organic halogenide, forming respectively aminomethyl and organylsulphide derivatives of piperidino-2-hydroxypropanethiol-3. Composition and structure of synthesized compounds are confirmed by elemental analysis and method NMR.

SYNTHESIS OF NEW AMINOMETHYL AND ORGANYLSULPHIDE DERIVATIVES OF PIPERIDINO-2-HYDROXYPROPANETHIOL-3