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Hipofiz bezinden adrenokortikotropik hormon ( ACTH) salgilayan adenom, endojen Cushing hastaliginin en sik gorulen nedenidir. Renal hucreli karsinom (RCC) en sik gorulen bobrek kanseridir ve bu kanser ile iliskili bircok endokrinolojik anormallik olabilir. Renal hucreli karsinom tanisi alan hastalarda Cushing sendromu saptanabilirken Cushing hastaligi cok nadir gorulur. Cushing hastaliginin tanisi klinik semptomlar, endokrinolojik testler ve radyolojik bulgularin degerlendirilmesi ile konur. Cushing hastaliginda en etkili tedavi adenomun rezeksiyonudur ama makroadenomlarda rezeksiyon ile kur sansi daha dusuktur. Postoperatif donemde kur saglanamamis olgularda tedavi secenekleri arasinda radyoterapi, medikal tedaviler (bromokriptin, siproheptadin, ketakonazol, pasireotide gibi) veya bilateral adrenalektomi dusunulebilir. Burada Cushing hastaligi ile birlikte renal hucreli karsinom tanisi konulan bir hasta sunulacaktir.

Case Report of a Rare Disease: Concomitant Renal Cell Carcinoma with Cushing's Disease