Open AccessThe Extracts of Epilobium Parviflorum Inhibit MCF-7 Breast Cancer Cells
Author(s) -
Bhenaz Hatefi Kia,
Sakineh Kazemi Noureini,
Mohammad Reza Vaezi Kakhki
Publication year - 2021
Publication title -
iranian journal of toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.208
H-Index - 2
eISSN - 2251-9459
pISSN - 2008-2967
DOI - 10.32598/ijt.15.1.752.1
Subject(s) - mcf 7 , cytotoxicity , cytotoxic t cell , traditional medicine , cancer cell , mtt assay , toxicity , ic50 , breast cancer , cell culture , prostate cancer , chemistry , growth inhibition , cancer , pharmacology , biology , in vitro , human breast , medicine , biochemistry , genetics
Methods: The root, aerial parts and flowers of the plant were, collected and dried separately at ambient temperature and away from direct sunlight. The aquatic and methanolic extracts of each part was prepared. The effect of each extract on the growth of MCF-7 breast carcinoma cells and HEK293 normal cell line was evaluated, using MTT assay. Each experiment was repeated at least three times independently. The IC50 values for each treatment time point were analyzed, using ANOVA at P<0.05.
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