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There is high occurrence of apical periodontitis in diabetes mellitus patients. The healing process of periapical tissue in diabetes is affected by the altered immunity. The aim of the study is to determine the periapical healing followed by endodontic therapy in type 2 diabetes mellitus and compare with non-diabetes Methodology: This review was directed as per the PRISMA and JBI guidelines. A total of  six articles published over a period of past 15 years were included in qualitative synthesis. Results: Total of 1424 articles were searched out of which 26  articles were selected after reading title and abstract. As a next step, full text papers were obtained. However studies in which periapical healing in type II diabetes and non- diabetes were selected. Finally a total of 26 articles were included out of which 20 articles were excluded on basis of insufficient data and 6 articles were selected for final synthesis. Conclusion: Patients with type II diabetes mellitus had slower healing rate compared to non-diabetes patients. Keywords: Type II diabetes mellitus, Non- Diabetes, Root Canal Therapy, Periapical Healing

A COMPARATIVE STUDY ON PERIAPICAL HEALING FOLLOWED BY ENDODONTIC THERAPY IN TYPE II DIABETES MELLITUS VS NON –DIABETES-A SYSTEMATIC REVIEW