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Surgical site infection (SSI) is defined as infection occurring in an incisional wound within 30 days of the procedure or within 1 year if a prosthesis is implanted. A few studies have reported a relationship between low serum albumin level and low cholesterol level in surgical site infection, length of hospital stay and death and is reported to be one of the major causes of morbidity and mortality among hospitalized patients. METHOD:1 year prospective cohort study was conducted in Tertiary Health care Centre, Indore. A study population of 248 patients from hospital admitted in Department of General Surgery for elective operation. RESULT:From Total Patients - 172 (69.4%) were male patients and 76 (30.6%) were female patients. The frequency of patients developed SSI in hypoalbuminemia was 25(44.6%) in number compare to n=18(10.7%) in normal and to n= 03(12.5%) in hyper albuminemia. The Relative Risk between Hypoalbuminemia and SSI is 4.17 with CI (2.46  to 7) (P = <0.001). There is a significant association between cholesterol levels and the occurrence of SSI, with majority of the people with SSI had Hypocholesterolemia and it was found to be statistically significant with Relative risk(RR=3.98, CI= 2.28 to 6.95) (P = <0.001). CONCLUSION:Low blood cholesterol and albumin level are the important factors which is usually can lead to significant decrease in this preventable post operative complications especially in a malnourished population presenting in a government setup.

ROLE OF PREOPERATIVE ASSESSMENT OF SERUM CHOLESTEROL AND ALBUMIN IN SURGICAL SITE INFECTION.