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This review aims to present magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) for applications in cellular therapeutics including descriptions of the use of F-19 MRI and F-19 MRS in drug tracking and visualization. Both MRI and MRS are often used as diagnostic tools in oncology, are non-invasive, and also can be employed for monitoring non-oncological and oncological therapies. Herein, we provide information pertaining to tracking and visualization of fluorinated drug uptake in cancer tissue in vitro, in vivo and ex vivo. The response of tissue to treatment is also discussed.

Selected applications of fluorinated MR contrast agents and fluorine-containing drugs in medicine