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Pompe disease (PD) causes a progressive muscular weakness and impairment of patients’ mobility. Many patients develop intolerance to exercise due to reduced activity and consequent decline in muscle function. Exercise training prevents physical deconditioning and muscle wasting. Enzyme replacement therapy (ERT) was recently introduced, and has modifi ed the course of the disease. Other therapeutic interventions, such as exercise training, have been proposed as possible countermeasures for muscle impairment in patients with late-onset PD. We report the results of a 12-week home exercise training program on functional capacity and quality of life in a 20-year-old male patient with PD receiving ERT for 2 years.

journal of neuromuscular diseases

Effects of Exercise Training on Functional Capacity and Quality of Life in a Patient with Late-Onset Pompe Disease Receiving Enzyme Replacement Therapy