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This study is a non-interventional correlation study. Two groups (n = 40), consisting of 20 LOPD patients and 20 healthy age-matched (HAM), individuals will have their gait patterns assessed by instrumented gait analysis (Qualisys OQUS). The aim of the study is to identify the differences in gait between LOPD patients and HAM individuals. The LOPD group will be recruited from the Mark Holland metabolic Unit, Salford Royal NHS Foundation Trust. The HAM participants will be recruited from across the normal population. Participants included in the study will have a genetic diagnosis of LOPD and will be able to walk unaided for a distance of 50–550 m in a 6-minute walk test (6MWT). All participants who have a diagnosis of a signifi cant musculoskeletal or neuromuscular condition will be excluded from the study. A Comparison of Gait Patterns between Late-Onset Pompe Disease and Age-Matched Healthy Individuals: Does Late-Onset Pompe Disease have a Typical Gait Pattern?

journal of neuromuscular diseases

A Comparison of Gait Patterns between Late-Onset Pompe Disease and Age-Matched Healthy Individuals: Does Late-Onset Pompe Disease have a Typical Gait Pattern?