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A brain atrophy and lesion index (BALI) based on high-field magnetic resonance imaging (MRI) has recently been validated to evaluate structural changes in the aging brain. The present study investigated the two-year progression of brain structural deficits in people with Alzheimer's disease (AD) and mild cognitive impairment (MCI), and in healthy control older adults (HC) using the BALI rating.

journal of alzheimer's disease

An MRI Brain Atrophy and Lesion Index to Assess the Progression of Structural Changes in Alzheimer's Disease, Mild Cognitive Impairment, and Normal Aging: A Follow-Up Study