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LEVEL OF EVIDENCE: 2B SUMMARY Background. Excessive uninterrupted sitting is found to be associated with increased cardiometabolic disease risk in desk-based employees. Point-of-choice prompts using a smartphone application (SmPh-app) may be a feasible method of promoting physical activity and negating cardiometabolic disease risk. The study aims to investigate the effectiveness of SmPh-app directed walk reminders on cardiometabolic disease risk (Fasting Blood Glucose (FBG), aerobic capacity (VO2 max) and Heart Rate Variability (HRV) in desk-based office employees. Methods. In this pragmatic, two-arm, parallel, cluster randomised trial, desk-based employees (n=53) of five administrative offices (clusters) of a university were randomised to two groups: SMART group in which employees were provided with SmPh-app based (six) walk reminders during working hours and CONTROL group in which employees continued their usual work. As FBG, VO2 max and HRV data were skewed, nonparametric statistical analyses were used for intention-to-treat analysis. Results. Of 53 desk-based employees initially included in the trial, 47 completed the four weeks trial. Employees in SMART group showed a statistically significant difference in FBG (p < 0.001), VO2 max (p < 0.05) and nearly all domains (time, frequency and non-linear) of HRV (prevs. post-intervention) compared to CONTROL group. SMART group employees were found to reduce FBG by 8 mmol/dL (interquartile range (IQR): -12.25 to -3.75 mmol/dL), improve VO2 max by 2.23 ml/kg/min (IQR: 0.12 to 4.34 ml/kg/min) and improve HRV in all the domains compared to CONTROL group. Conclusions. SmPh-app based walk reminders improved FBG, functional capacity and HRV in desk-based office employees.

m.l.t.j. muscles, ligaments and tendons journal

Effectiveness of A Smartphone Directed Physical Activity Program on Cardiometabolic Disease Risk in Desk Based Office Employees. A Pragmatic, Two Arm, Parallel, Cluster Randomised Trial