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We isolated a New Delhi metallo-β-lactamase 5 (NDM-5)-producing Klebsiella pneumoniae sequence type (ST) 258 strain in southwest China during 2017. The bla NDM-5 gene was acquired by horizontal plasmid transfer from NDM-5-producing Escherichia coli. We identified genomic characteristics in ST258 strains that differed from those of global K. pneumoniae carbapenemase-producing strains.

New Delhi Metallo-β-Lactamase 5–Producing Klebsiella pneumoniae Sequence Type 258, Southwest China, 2017