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These are the first reported human cases of West Nile fever in Central Europe (5); an extensive outbreak occurred in Romania in 1996, with approximately 500 patients hospitalized and a 4% to 8% fatality rate (6,7). West Nile virus should be viewed as a potential agent of local sporadic cases, clusters, or outbreaks, even in temperate Europe. Environmental factors (including human activities) that enhance vector population densities (heavy rains followed by floods, irrigation, higher than usual temperatures due to global warming) might produce an increased incidence of West Nile fever and other new or reemerging mosquito-borne diseases. Surveillance for West Nile fever should monitor population density and infection rate of principal vectors, antibodies in vertebrates and exposed human groups, and routine diagnosis of human infections.

Ofloxacin-ResistantVibrio choleraeO139 in Hong Kong