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Kahramanmaras Sutcu Imam Universitesi Saglik Uygulama ve Arastirma Hastanesi’nde kan kulturlerinden izole edilen mikroorganizmalar ve antibiyotik duyarliliklari OZET Amac: Kan dolasimi enfeksiyonlari, mortalite ve morbiditenin onde gelen nedenlerinden biridir. Calismamizin amaci kan kulturlerinde en sik belirlenen enfeksiyon etkenlerini ve antibiyotik duyarliliklarini saptamaktir. Gerec ve Yontem: 3719 izolat calismaya dahil edilmistir. Kan kulturu ornekleri BACT/ALERT 3D otomatize sistemi ile inkube edilmistir. Ureyen mikroorganizmalarin identifikasyonu ve antibiyotik duyarliliklari Phoenix otomatize sistem ile yapilmistir. Bulgular: En sik izole edilen Gram negatif bakteriler Escherichia coli 227 (%36.37), Klebsiella pneumoniae 126 (%20.19) olarak bulunmustur. Gram pozitif bakterilerin 2245’inin koagulaz negatif Staphylococcus turleri, 251’inin (%8.8) Enterococcus spp., 194’unun (%6.87)  Staphylococcus aureus oldugu saptanmistir. Gram negatif bakterilere en etkili antibiyotikler karbapenemler, aminoglikozidler ve tigesiklin olarak bulunmustur. Tum Acinetobacter izolatlari karbapenemlere direncli bulunmustur. Staphylococcus aureus izolatlarinda vankomisin direnci saptanmazken metisilin direnci %55, koagulaz negatif Staphylococcus izolatlarinda metisilin direnci %84 olarak bulunmustur. Enterococcus spp. izolatlarinda vankomisin direnci %9.7 olarak bulunmustur. Sonuc: Sonuc olarak bakterilerin direnc oranlarinin bu denli yuksek olmasi enfeksiyon kontrol onlemlerinin artirilmasi gerektigini dusundurmektedir. Anahtar kelimeler : Antibiyotik direnci; kan kulturu; kan dolasimi enfeksiyonu; mikroorganizma Microorganism isolated from blood culture and their antimicrobial susceptibilities obtained at Kahramanmaras Sutcu Imam University Health Practice and Research Hospital ABSTRACT Objective: Blood stream infections remain a major cause of morbidity and mortality. The aim of this study is to determine the types of microorganisms and antibiotic susceptibility isolated from blood cultures. Materials and Methods: 3719 isolates identified included in the study. Blood culture samples were incubated in BACT/ALERT 3D automated system. Identification and antibiotic susceptibility of microorganisms were done with Phoenix automated system. Results: The most frequent Gram negative bacteria were  Escherichia coli 227 (36.3%), Klebsiella pneumoniae 126 (20.1%). The most frequent Gram positive bacteria were 2245 (79.5%) coagulase negative Staphylococcus , 251 (8.8%) Enterococcus spp., 194 (6.87%)  Staphylococcus aureus . Carbapenems, aminoglycosides and tigecycline were most effective antibiotics against all Gram negatives. All Acinetobacter isolates were resistant to carbapenems. No resistance to vancomycin was detected Staphylococcus aureus . Methicilin resistance was 55% to Staphylococcus aureus , 84% to coagulase negative Staphylococcus . Vancomycin resistance was 9.7% to Enterococcus spp.. Conclusion: As a result, the high resistance rates of bacteria suggest that infection control measures should be increased. Key words : Antibiotic resistance; blood culture; blood stream infection; microorganism

sakarya tıp dergisi

Kahramanmaraş Sütçü İmam Üniversitesi Sağlık Uygulama ve Araştırma Hastanesi’nde Kan Kültürlerinden İzole Edilen Mikroorganizmalar ve Antibiyotik Duyarlılıkları