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The article considers the processes of synthesis of water-soluble polymers HPAA-HP (hydrolyzed polyacrylamide with the modifier hydrogen peroxide), HPAA-MEA (hydrolyzed polyacrylamide with the modifier monoethanolamine), HPAA-TEA (hydrolyzed polyacrylamide with the modifier triethanolamine). The physical and chemical properties of water solutions of water-soluble polymers are investigated. It is shown that they are highmolecular polyelectrolytes. The compatibility of polymers with antibiotics is shown. Synthesized polymers have been proposed as ointments of soft carriers for use with medications. Many known ointment bases are easily exposed to microbial contamination (hydrogenated fats, fatty and vegetable oils, gelatin gels and others). The effect of the antibacterial ointments we are researching is aimed at the destruction of pathogenic microorganisms and products of their vital activity, which are the cause of infectious and inflammatory processes in the wound. Therefore, one of the most important requirements expressed to ointment bases, is resistance to microbial contamination, because the latter can significantly reduce the concentration of antibiotics in ointments, thereby reducing the therapeutic effect of the preparations, and can be the cause of secondary infection of the wound or burn surface. The study of colloidal-chemical properties of aqueous solutions of the studied polymers allowed establishing the relationship between poly electrolyte effects and functional composition, the degree of hydrolysis. The conditions for obtaining HPAA-HP, HPAA-MEA polymers, most clearly showing polyelectrolyte properties were determined based on the research of physical and colloidal chemical properties, their polyelectrolytic character is revealed.and they belong to high-molecular surfactants they relate to high-molecular surface-active substances.

THE STUDY OF PHYSICAL AND CHEMICAL PROPERTIES OF WATER-SOLUBLE POLYMER REAGENTS AND THEIR COMPATIBILITY WITH ANTIBIOTICS