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The main goal of this study is to compare reactivity and stability of eugenol (1), methyl eugenol (2), and eugenyl acetate (3) in sulfonation reaction to produce new fused ring sultone derivatives. Isolated eugenol can be easily derivatised to methyl eugenol (2) and eugenil acetate (3) using dimethyl sulfate and acetate anhydride respectively. Eugenol (1), methyl eugenol (2), and eugenil acetate (3) separately react with chlorosulfuric acid to produce new fused ring sultone derivatives in different yields. Methyl eugenol (2) gave a more stable product compare to eugenol (1) and eugenyl acetate (3).

SYNTHESIS OF NEW FUSED RING SULTONE FROM EUGENOL AND ITS DERIVATIVES