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Background: COVID-19 pandemic has been one of the greatest challenges to the global healthcare system Although the respiratory system is the main target of SARS-CoV-2 infection;other organs, exposure to the viral infection might also be a concern for CVID-19 affected patients especially the cardiovascular system and liver Objective: To know the status of C-reactive protein (CRP)and Liver Function Tests (LFT) in Covid-19 positive patients before initiating any treatment in a tertiary care hospital Methods: Age and sex-matched 40 cases were taken for the study who were hospitalized and COVID-19 infection had been confirmed by real-time RT PCR for COVID-19 Patients with a previous history of liver illness, renal disorders, chronic inflammatory conditions, malignancy and autoimmune disorders were excluded from the study Results: Almost all the liver enzymes were higher than the normal levels as seen in aspartate transaminase (35%), alanine transaminase (22 5%), alkaline phosphatase (20%), and gamma-glutamyl transaminase (35%) And whenever the protein, especially albumin was low there was an increased value of CRP and correspondingly with increased total and direct bilirubin levels Conclusion: In our study liver function test was altered even before starting any treatment for SARS-CoV-2 indicates that LFT can be a tool to assess multiorgan involvement whenever the patient is going for complication or cytokine storm by doing serial measurements of liver function ©@IJCRR

international journal of current research and review

A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study