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Oral squamous cell carcinoma (OSCC) is the eighth most common cancer worldwide and ranks among the top three cancers in India. OSCC primarily occurs in males in their 5th to 8th decade of life.1 However, based on the recent study in Europe an increase in the evidence of OSCC has been observed in younger adults with no history of tobacco and alcohol.2,3 There is also an increase in the incidence among females.24 While tobacco and smoking are well-established etiological factors for the development of OSCC, non-smoking, and non-drinking patients with OSCC have been identified in the literature as a unique and growing subgroup.5,6 In contrast to the general predilection for males in OSCC, the Non-habit-associated OSCC has a female preponderance, young mean age, and the carcinoma is more likely to be in the oral cavity than in the other site.5,7,8 The Non-habitassociated OSCC population currently represents about 13 to 35% of the OSCC population, although this may increase as tobacco use decreases.9

Prevalence of Non-Habit-Associated Oral Squamous Cell Carcinoma and its Site Predilection - A Retrospective Institution Based Study