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Colorectal Cancer (CRC) is still a big problem in the world in general and in Indonesia in particular. CRC is the third most common cancer of all cancers and the second leading cause of cancer-related deaths for men and women in the United States. According to the American Cancer Society, 135,430 new cases, and 50,260 deaths from colorectal cancer are estimated to occur in 2017, and the lifetime risk of developing a CRC is around 1 in 21 (4.7%) for men and 1 in 23 (4.4%) for the woman. In Indonesia, the incidence of colorectal cancer is 12.1 per 100,000 adult population, with a mortality of 9.1% of all cancer cases.1,2 Comprehensive management of CRCs is very important because of the high number of cases and high mortality rates with high health care costs. The CRC treatment strategy is chemotherapy and surgery. Local tumor control by surgery is generally the main treatment to prevent local tumor complications, such as postoperative obstruction, perforation or leakage of anastomosis, fistula formation, and infection. Even with metastases in the liver or lungs, primary tumor resection remains a priority.3

Relationship of Neutrophil-to-Lymphocyte Ratio with Anastomosis Leakage as Complication of Colorectal Surgery in Colorectal Cancer Patients