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Shutter-speed model analysis of dynamic contrast-enhanced MR imaging allows estimation of mean intracellular water molecule lifetime (a measure of cellular energy metabolism) and volume transfer constant (a measure of hemodynamics). The purpose of this study was to investigate the prognostic utility of pretreatment mean intracellular water molecule lifetime and volume transfer constant in predicting overall survival in patients with squamous cell carcinomas of the head and neck and to stratify p16-positive patients based upon survival outcome.

american journal of neuroradiology

Dynamic Contrast-Enhanced MRI–Derived Intracellular Water Lifetime (τ<i><sub>i</sub></i>): A Prognostic Marker for Patients with Head and Neck Squamous Cell Carcinomas

Dynamic Contrast-Enhanced MRI–Derived Intracellular Water Lifetime (τi): A Prognostic Marker for Patients with Head and Neck Squamous Cell Carcinomas

Dynamic Contrast-Enhanced MRI–Derived Intracellular Water Lifetime (τ_i): A Prognostic Marker for Patients with Head and Neck Squamous Cell Carcinomas