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As yet, there are no in vivo data on tissue water changes and associated morphometric changes involved in the osmo-adaptation of normal brains. Our aim was to evaluate osmoadaptive responses of the healthy human brain to osmotic challenges of de- and rehydration by serial measurements of brain volume, tissue fluid, and metabolites.

Responses of the Human Brain to Mild Dehydration and Rehydration Explored In Vivo by1H-MR Imaging and Spectroscopy

Responses of the Human Brain to Mild Dehydration and Rehydration Explored In Vivo by¹H-MR Imaging and Spectroscopy