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It has been suggested, on the basis of a previous pilot study conducted in a small number of patients, that MR imaging-based PVE correction in I-123 iomazenil brain SPECT improves the detectability of cortical epileptogenic foci. In the present study, we performed an investigation by using a larger sample size to establish the effectiveness of the PVE correction and to conduct a detailed evaluation based on the histologic classification of lesions.

american journal of neuroradiology

MR Imaging–Based Correction for Partial Volume Effect Improves Detectability of Intractable Epileptogenic Foci on Iodine 123 Iomazenil Brain SPECT Images: An Extended Study with a Larger Sample Size