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Quantitative MR imaging techniques allow detection of subtle tissue changes that occur with brain aging beyond the accumulation of WMH and brain atrophy. To what extent sex and cerebrovascular risk factors impact these changes is largely unknown. We attempted to study these risk factors in the context of the community-based ASPS.

american journal of neuroradiology

The Impact of Sex and Vascular Risk Factors on Brain Tissue Changes with Aging: Magnetization Transfer Imaging Results of the Austrian Stroke Prevention Study