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Arterial selection for reference time-enhancement curve generation in deconvolution-based perfusion CT (PCT) studies of the head and neck is under-evaluated. This study of 11 patients with confirmed head and neck squamous cell carcinoma demonstrates significant correlation (range, r = 0.85-0.95) between perfusion parameter values derived with internal carotid artery (ICA) as compared to an external carotid artery reference, supporting the use of the ICA as arterial reference in PCT studies of the neck.

CT Perfusion of the Neck: Internal Carotid Artery versus External Carotid Artery as the Reference Artery