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A substantial proportion of women with gonococcal infection are asymptomatic but symptomatic in male. Thus in developing countries, problem arises in active case detection where laboratory facilities for testing are limited. During the study, the diagnostic validity of the hierarchial clinical algorithm as well as that of a nonhierarchial scoring system were assessed among 102 patient visiting at Dermatology/ Venerology (DV) and Gynecology(Gynae) out patient department(OPD) of Tribhuvan University Teaching Hospital (TUTH), Kathmandu, Nepal. In the study period of 8 months, May –December 1999, 9 (8.82%) were infected with N. gonorrhoea & 2(1.96%) with Gram Negative intracellular diplococci. Age group of 20-30 years were found to be more infected followed by age groups 30-40 years & 40-50 years ( P< 0.10). The male were found to be predominantly infected than female and married were found to be more infected than unmarried. Among the infected people most of them had secondary level education and least of them had higher level education. Service holders were found to be more infected than farmers, drivers & others. But male service holders & housewives were equally infected. Antimicrobial susceptibility of N. gonorrhoea showed 100% susceptible to Ceftriaxone, followed by Ciprofloxacin (88.88%) whereas 22.22% resistant to Tetracycline, 55.55% to Cotrimoxazole and 55.55% to Penicillin. Among isolates, 33.33% were ßlactamase producer. Co-micro organisms like Candida spp and Staphylococcus spp were also observed. 1. Research Officer, Infectious and Tropical Disease Research Centre, Tripureshwor, Kathmandu, Nepal. 2. Associate Professor, Head of Department, Clinical Microbiology, Institute of Medicine, TUTH, Nepal. 3. Professor, Central Department of Microbiology, Kirtipur, Kathmandu, Nepal. 4. Associate Professor, Department of Obstetrics/ Gynecology Department, Institute of Medicine, TUTH, Nepal. 5. Assistant Professor , Head of Dept., Dermatologist, Venerologist & Leprologist, Dept. of Dermatology/Venerology, Institute of Medicine, TUTH, Nepal. Address for correspondence : Binita Panta, Research Officer, Infectious and Tropical Disease Research Centre, Tripureshwor, Kathmandu, Nepal. P.O. Box: 8973, NPC 565 Tel: 493680 (Res.), Email: gyan@col.com.np ORIGINAL ARTICLE Journal of Nepal Medical Association, 2001:40:12-17 Panta B, Tuladhar N R Sharma A P, Sharma J, Jha A K

journal of nepal medical association

PREVALENCE OF GONOCOCCAL INFECTION AMONG THE PATIENTS VISITING AT DERMATOLOGY/VENEROLOGY AND GYNAECOLOGY DEPARTMENT OF TRIBHUVAN UNIVERSITY TEACHING HOSPITAL