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In Nepal a total number of 27584 Japanese encephalitis (JE) cases and 5382 deaths have been reported with an average case fatality rate of 19.5% in aggregate since 1978 to 2004. Past trend of the disease has shown that JE outbreaks are circumscribed and do not cover large areas. However it depends on the flight range of the vector mosquitoes presence of pigs as an amplifying hosts and the presence of a susceptible human population. During twenty six years period of time the highest number of cases were reported in 1997 (2953 cases) and the second highest were in 1999 (2924 cases). Similarly highest number of cases was reported from Far-western and Mid-western Development Regions. The lowest number of cases (54 cases) with mortality (CFR 29.6 percent) has been reported during the year 1981. The highest case fatality was observed in 1982 (CFR 46.3 percent). The overall mortality of JE varies from 8.5 percent (2004) to 46.3 percent (1982). (excerpt)

Should Vaccination be a Priority Approach for Japanese Encephalitis Prevention in Nepal ?