English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Object  The authors conducted a study to determine population-based estimates of survival following the diagnosis and treatment of nonmalignant intracranial meningioma in the US in the modern era.    Methods  Patients with nonmalignant intracranial meningioma were identified through the Surveillance, Epidemiology, and End Results (SEER) database for the years 2004–2007. Predictors of undergoing resection were identified and odds ratios calculated. Estimates of survival were calculated using Kaplan-Meier estimation method and Cox proportional hazards model.    Results  There were 12,284 patients with a diagnosis of nonmalignant intracranial meningioma included in the analysis. Only 55% had histological confirmation of the diagnosis of nonmalignant meningioma. Resection was used as an initial treatment in 43% of cases. Patients treated with surgery were more likely to be younger (OR 9.3, 95% CI 8.1–10.7, for resection in patients age 40–59 years compared with age &gt; 80 years), male (OR 1.4, 95% CI 1.3–1.5, for males compared with females), white (OR 0.8, 95% CI 0.7–0.9, for black patients compared with white patients), and have larger tumors (OR 11.8, 95% CI 10.3–13.6, for tumors of the largest quartile compared with the smallest quartile). Patients treated with resection had a 3-year postdiagnosis survival estimate of 93.4% (95% CI 92.5%–94.3%) compared with 88.3% (95% CI 85.5%–90.6%) in patients not treated with resection (p &lt; 0.01). Younger patient age, female sex, unilateral tumors, and resection were predictors of improved postdiagnosis survival after multivariate adjustment in patients with histologically confirmed meningiomas.    Conclusions  This analysis represents the first modern population-based analysis of treatment patterns and outcomes in US patients with nonmalignant intracranial meningioma. Over 85% of patients survive 3 years after diagnosis, and resection is associated with improved survival.

journal of neurosurgery

Treatment and survival of patients with nonmalignant intracranial meningioma: results from the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute