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Decreased activities of Na+, K+-ATPase in liver and kidney, Mg2+-ATPase in kidney, and Ca2+-ATPase in liver were observed in alcoholic rats (3.0g of ethanol/kg body weight, 30% [v/v]) given twice daily for 30 days compared with those of the controls. Increased activities of Ca2+-ATPase in kidney and Mg2+-ATPase in liver were also observed in the alcoholic rats. All the above metabolic alterations induced by alcohol were effectively avoided by L-cysteine (20mg/100g body weight) given twice daily for 30 days.

In vivo Effect of L-Cysteine on Ethanol-Induced Alterations in Membrane-Bound ATPases of Liver and Kidney of Experimental Rats.