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Using electron microscopic studies, the structural and functional reorganization of the neck skin and mucous membrane in patients with malignant tumors of the oral cavity at various stages of combined treatment is presented. Significant violations of tissue and cellular elements, their ultastructures, especially fibroblasts, intercellular substance of connective tissue and vessels of the microcirculatory bed were revealed, which exhausts the volume of compensatory and adaptive capabilities of tissue and cells included in the irradiation zone. The degree of structural and functional disorders in irradiated tissues is proportional to the amount of SOD.

MORPHOLOGICAL AND ELECTRON MICROSCOPIC CHARACTERISTICS OF THE SKIN AND MUCOUS MEMBRANE AT VARIOUS STAGES OF COMBINED TREATMENT OF ORAL CANCER