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Primary functions of kidneys to filter the blood by its cells called nephrons, products after metabolism and toxics produced by kidneys upper Urinary tract;  and stored in Lower Urinary tract; this helps the body for balance of, electrolytes, water, RBCs, leukocytes, ca and blood pressure. If the renal system not work properly it may cause some complications like kidney stones, electrolytes imbalance, which leads to different complications some time may leads to kidney failure .it also effects on blood cells, if kidneys not work properly our body retains water and toxics not excreted form blood steam, so patient may leads to death. The prevalence of kidney diseases is significantly increasing in pediatric population, that is   may be due to life style changes i.e. diet changes, environmental changes. .

Impacts of renal insufficiency on hepatic profile among different chronic Lower Urinary tract; patients in Quetta