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Coronavirus disease 2019 (COVID-19) is arguably the most socially and economically disruptive pandemic since the 1918 influenza pandemic. Although pediatric COVID-19 shares features with the adult disease, there are several differences. Children produce virus in amounts at least equal to adults, if not higher and can transmit the virus just as adults can. School-aged children are generally less severely affected than infants or adults, but some children without significant underlying disease become ill or die in a disease process analogous to the one most commonly seen in adults as severe pulmonary disease and respiratory failure. Children and adults appear to have different humoral immune responses to COVID-19.

biomedical research and clinical reviews

Effective, timely use of Intravenous Immunoglobulins for management of Pediatric multisystem inflammatory syndrome associated with COVID-19 (PMIS-COV19) in a 9 years old boy: Case report