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Rationale: COVID-19 infection is a wide-world pandemic serious highly infectious multisystem disease. Neurological, cardiovascular, hepatic, and renal systems are commonly involved. Connected aircraft squadron electrocardiographic sign (Yasser’s sign) is a novel electrocardiographic sign which a relevant to T-wave changes and respiratory rate. This sign is a strong guide for tachypnea. QTc-interval prolongation is a serious signal for torsades de pointes, fatal ventricular tachyarrhythmias, and sudden death. Previously, fragmentation of the QRS-complex had already been considered a marker for structural heart diseases (SHD) triggering cardiac hypertrophy.  Patient concerns: An 88-year-old, carpenter, smoker, married Egyptian male patient was admitted to the critical care unit with cerebrovascular stroke, cardiac involvement, and COVID-19 pneumonia.   Diagnosis: COVID-19 pneumonia with acute neurological events and cardiovascular involvement.   Interventions: Electrocardiography, oxygenation, non-contrasted chest CT, and brain CT.   Outcomes: Good response and better outcomes despite the presence of several remarkable risk factors were the results.   Lessons: The clinical and electrocardiographic response after using anti-COVID19 measures the signifying its role and suggest the diagnosis of COVID19 infection. The presence of COVID-19 pneumonia, stroke, QTc-interval prolongation, fragmentation of the QRS-complex, hypocalcemia, Connected aircraft squadron electrocardiographic sign (Yasser’s sign) with severe fatigue, elderly, and cigarette smoking are prognostic factors for the severity of the disease.

international journal of clinical case reports and reviews

An Elderly COVID-19 Pneumonia with Stroke, and QTc Prolongation, Fragmentation of the QRS-complex, and Connected Aircraft Squadron Electrocardiographic Sign (Yasser’s sign); Multiple Risk and Serious Implications