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Genetic factors play a substantial role in acute myeloid leukemia (AML) etiology. Overexpression of the mouse double minute 2 (MDM2) gene has been explored in many tumors. However, the role of MDM2 -309T&gt;G (rs2279744) polymorphism in AML remains unclear. We have performed this study to examine the association of MDM2 -309T&gt;G with AML in an Iranian population.

Association of Mouse Double Minute 2 -309T>G Polymorphism with Acute Myeloid Leukemia in an Iranian Population: A Case- Control Study