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A Visualization Technique for Gene Networks with Edge Bundling Rina Nakazawa, Takayuki Itoh, Jun Sese and Aika Terada ABSTRACT Gene networks have been constructed with genes as nodes and interactions between genes as edges. Because edges whose both ends have different functions may indicate important functional connections, visualization of the functional connection in the network helps us to understand cellular mechanisms. However, very numerous nodes and edges in the gene networks prevent the exploration of the relations from the visualization, if it is visualized by traditional techniques. In this paper, we introduce a simultaneous visualization of a large gene network and gene functions provided by gene ontology (GO) consortium. By bundling edges between groups whose genes have similar function, complication connections and many crossing edges between groups are represented as essential thick edges, resulting easily understanding of connections between gene functions.