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Background: Pulmonary mucormycosis is a rare and aggressive fungal infection that is known to predominantly affect immunocompromised hosts. Early surgical resection with prolonged antimycotic therapy is an established therapy for localized disease; however, the role of surgery in multifocal pulmonary disease is less clear. Case: We report successful treatment of medically refractory disseminated pulmonary mucormycosis with a salvage lobectomy and intrapleural antibiosis in a 58-year-old immunocompromised female. Conclusion: Surgery resection of necrotic foci in disseminated pulmonary mucormycosis is a viable surgical treatment option even if extensive resection is required. This treatment option should be considered early, given the high incidence of medically refractory disease.

Surgical Management of Disseminated Pulmonary Mucormycosis in the Immunocompromised