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Objective: We reviewed the surgical outcomes of minimally invasive esophagectomy (MIE), especially thenumber of lymph nodes retrieved, for the patients with esophageal cancer to clarify the surgical benefits ofMIE in patients with esophageal cancer.Material and Methods: A systematic literature search was performed, and articles that fully described thesurgical results of MIE were selected. Parameters such as operative time, blood loss, the number of lymphnodes retrieved, and postoperative complications were compared among patients undergoing minimallyinvasive esophagectomy (MIE) in the left lateral decubitus position (MIE-LP), MIE in the prone position(MIE-PP), and open thoracic esophagectomy (OE).Results: The conversion rate from MIE to OE was very low. MIE-PP was associated with lower blood lossthan OE and MIE-LP. Results of a multicenter randomized controlled trial demonstrated that pneumoniaand recurrent laryngeal nerve paralysis in MIE-PP significantly reduced compared with OE. Althoughpostoperative complications were not different between MIE-PP and MIE-LP, the number of lymph nodesretrieved in MIE-PP was higher than that in MIE-LP.Conclusion: MIE-PP has potential benefits in terms of less surgical invasiveness and improvement ofmediastinal lymph node dissection. A prospective randomized control trial using a large number of casesand long-term follow-up is recommended for analyses of appropriate mediastinal lymph node dissectionand its impact on oncological benefit.

journal of surgical oncology

Surgical Benefits of Prone Position Thoracoscopic Esophagectomy Over Open Thoracic and Thoracoscopic Esophagectomy in Left Lateral Decubitus Position: A Literature Review