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In the previous study, we evaluated the protective eficacies of the folowing three vaccines for the thread-sail filefish Stephanolepis cirhifer: a commercial Streptococcus iniae vaccine, a commercial Lactococcus garvieae vaccine and a combination of these two vaccines. In this study, we examined the three vaccines for the thread-sail filefish in terms of protective duration, protection against various heterogeneous strains of S. iniae and L. garvieae, and the efects of diferent water temperatures on the protection. The vaccines induced strong protection against heterogeneous strains of S. iniae and L. garvieae, and the protection was observed for 52 weeks after the vaccination. These vaccines also induced protective immunity when administrated at 15°C, 20°C and 25°C.

Pharmacological Characteristics of the Formalin-Killed Vaccines against Streptococcus iniae and Lactococcus garvieae in Farmed Thread-sail Filefish