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Materials and methods: examined 67 patients with chronic pyelonephritis. All patients were determined level of zinc in the blood and levels of inflammatory cytokines, C-reactive protein in the urine.&#x0D;Results. We found a significant decrease in the level of zinc in the blood of patients with chronic pyelonephritis (p 0.05), and the application of basic therapy in combination with zinc sulfate significantly increased (p&lt;0.05) and almost no difference in the values of group norms. Analyzing changes in cytokines and CRP in urine during treatment, we found a significant decrease in these indicators as the application of basic care and the application tested therapy, but the application of the second we found a greater decrease in these indicators, in some cases reaching values of group norms.&#x0D;Conclusions. The preparation of zinc may be a promising direction of the treatment of chronic pyelonephritis, since increases this microelement in the blood and reduces the activity of inflammatory response in the kidney.

STUDY OF INFLUENCE ZINC LEVEL IN BLOOD IN PATIENTS WITH CHRONIC PYELONEPHRITIS ON THE ACTIVITY OF INFLAMMATORY PROCESSES IN KIDNEYS