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In aqueous acidic media, picolinic acid, 2,3-dipicolinic acid, and 2,6-dipicolinic acid promoted Cr(VI) oxidation of lactose to lactobionic acid has been carried out at room temperature. A possible reaction mechanism, which is based on the kinetic results and the product analysis, has been proposed. The anionic surfactant sodium dodecyl sulphate (SDS) and nonionic surfactant Triton-X-100 (TX-100) accelerate the process while the cationic surfactant  N -cetylpyridinium chloride (CPC) retards the reaction.

Combination of Best Promoter and Micellar Catalyst for Cr(VI) Oxidation of Lactose to Lactobionic Acid in Aqueous Medium at Room Temperature