English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Taxus baccata L., yew, is dioecious, small to medium-sized evergreen tree, native to Europe, Africa and Asia, but it is cultivated worldwide because of its ornamental features. It is long known that all parts of yew (except for aril) are toxic, due to the alkaloid taxine. Nevertheless, some parts of yew tree can be used to treat cancer and as antimicrobial agents. Unlike its antibacterial properties, antifungal activity of T. baccata is poorly investigated. In this research, antifungal activity of yew methanolic and aqueous extracts was tested against Candida albicans ATCC 10231, Aspergillus brasiliensis ATCC 16404, and Ascosphaera apis MUCL 30769, through the agar well diffusion method. Leaves, bark and reproductive structures extracts were prepared separately for male and female plants. Unlike the aqueous, methanolic extracts caused variable degree of fungal growth inhibition. The strongest inhibition was observed in the activity of the aril extract against A. brasiliensis and C. albicans, with the activity of the male bark extract against A. apis following close. Considering the emerging multidrug resistance in C. albicans, an interesting finding is the inhibition of this species by all tested methanolic extracts, which is significantly stronger in comparison to the inhibition by standard antimycotic solution. According to the available data, male reproductive structures of this species were not tested earlier for their antifungal activity, and our study showed high level of antifungal activity of methanolic microstrobili extract.

New insights into the antifungal activity of Taxus baccata L.