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Male mice (11 months old) were fed 5% lard, fish oil, or kazunoko (salted fish roe product) lipids for 4 months to investigate the effects of diet on plasma glucose and adipocytokines. Plasma glucose levels were significantly lower in the fish oil group than in the lard group and there was a non-significant tendency towards lower levels in the kazunoko lipid group. Plasma leptin and adiponectin levels were also significantly higher in fish oil group than in lard group and resistin levels were significantly lower in the kazunoko lipid group than the lard group, but not the fish oil group. The results suggest that kazunoko lipids might be effective as a dietary component in the prevention of coronary heart disease and diabetes even though the metabolic effects of kazunoko lipids were different from those of fish oil.

A Comparative Study of Lipids Extracted from Herring Roe Products and Fish Oil on Plasma Glucose and Adipocytokine Levels in ICR Aged Mice