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Ayurvedic preparations containing varying amounts of Cannabis are freely available in Sri Lanka. These narcotic preparations are being abused by youngsters including school children which poses a threat not only to their health but also to society. However current narcotics legislation in Sri Lanka does not cover these preparations. "Nadana Modakaya" (MN) is the most popular preparation currently available. The aim of this study was to develop a method to quantify the t;.9_ Tetrahydrocannabinol (6 9-THC) levels in MM, to use this method to analyse market samples and to study how the manufacturing process affected the final level of t;.9-THC in the product. It is hoped that this data will enable the authorities to legislate for permissible levels of 69-THC in MN, and that the method developed would be used as the official method of analysis. A method to quantify 69-THC in MM was developed. The method which involved solvent extraction and column chromatography followed by GC, was validated by the standard addition recovery method. In the study of the methods for the preparation of MM, TLC densitometry was used

AYURVEDIC PREPARATIONS CONTAINING CANNABIS - SOME ANALYTICAL ASPECTS OF PHARMMX)L()CICAL AND LEGAL IMPORTANCE