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Fl Introduction 2 Geologic Setting 4 Fluid Inclusions 7 Sulfur Isotope Geothermometry 9 Biomarkers 12 Fluidand Heat-Flow and Thermal Maturity Calculations 18 Boundary Conditions and Grid 18 Depth of Burial 23 Permeability, Porosity, Fracture Zone Width, and Fluid Flux  23 Thermal Properties 25 Results 25 Calculated Duration of Hydrothermal Flow 25 Sources of Error 25 Discussion 28 Implications for Regional Fluid Flow  29 Sources of Salt 32 Conclusions  32 References Cited 32

Fluid inclusions and biomarkers in the Upper Mississippi Valley zinc-lead district; implications for the fluid-flow and thermal history of the Illinois Basin