English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

From suckling up to slaughter, pigs experience frequently enteritis outbreaks caused by various pathogens, most of them from bacterial origin. Preliminary epidemiological studies have shown that Escherichia coli are the most often isolated bacteria during diarrhoeas. Quinolones and penicillins are the most frequently used treatments when colibacillosis is suspected. Many reports have shown these bacteria became frequently resistant when these antibiotics were massively used. Moreover, many cross resistances were demonstrated in these antibiotiC families, leading to a major zootechnical and zoonotic concern. However, some antibiotics, like colistin , are effective to treat swine enteritis while they are known to involve no or few resistance. This article discusses some trial results that illustrate the observation of particular mechanisms of resistance of colistin that make it less susceptible to antibiotic resistance. In an experiment on the efficacy and safety of colistin for the treatment of colibacillosis in weaned piglets in an infected environment, no resistant strain of E. coli against colistin were isolated on rectal swabs after the treatment. Colistin ts not only clinically effective alternatives to quinolones and penicillins for the treatment of swine colibacillosis but also its use does not involve any antibiotic resistance profile. Colistin is therefore of great in terest to overcome the situation of antibioresistance currently established in the intensive swine production after a massive use of the more traditional antibiotics, ammostdes and macrolides, that can lead to a major risk for human health.

Colistin: alternative for the treatment of swine colibacillosis with the respect of human health protection