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The effect of diet on performance, viremia, and ontogeny of the humeral antibody response against porcine reproductive and respiratory syndrome virus (PRRSV) infection was evaluated in weaned pigs. In three replicates, weaned pigs (18 ± 1 d of age) from a PRRSV-naYve herd were randomly allotted to one of four pens (diets) in two rooms, each pen containing five pigs. Pigs (pens) began one of four dietary treatments 1 wk prior to inoculation with PRRSV: 1) basal diet plus carbadox (0.055 g/kg); 2) basal diet plus Echinacea 2% (2% of the total diet); 3) basal diet plus Echinacea 4% (4% of the total diet); and 4) basal diet composed of com, soybean meal, whey, and essential vitamins and minerals. Echinacea purpurea was purchased in powder form and determined by chemical analysis to contain 1.35% cichoric acid. Seven days after starting the diets ( d 7), all pigs in The authors gratefully acknowledge support of this project by the Leopold Center for Sustainable Agriculture, Hatch Act funds, and State of Iowa funds; Bev Fowles for her work in serology, Dianne McDonald at LID IF for her patience throughout the trial, and employees at the swine nutrition fann, Sally Medford, Pat Horton, Linda Mosman, Trevor Lutz, and Richard Evans. Also, thanks to Brian Wheeler, John Gilbert, Arlie Penner, Nicole Will, Dennis Horter, Kurt Krumm, Colin Johnson, and Charlwit Kulchaiyawat for their help in data and sample collection. Correspondence: (phone: 515-294-4621; fax: 515-294-6210; E-mail: honeyman@iastate.edu).

The effects of feeding Echinacea purpurea to nursery pigs on performance and viremia